反应详情

A solution was prepared from 12.9 g of 2-(4-nitrophenyl)butanol and 250 ml of absolute ethanol, 0.65 g of 10% palladium on charcoal catalyst was added and the mixture was hydrogenated in a Parr apparatus at about 2.7 atmospheres for 2 hours. The catalyst was removed by filtration and the solvent was evaporated from the filtrate to leave a crude oil which was purified by kugelrohr distillation (115° C. at 0.2 mm pressure) to give 2-(4-aminophenyl)butanol as a clear-white liquid.

1. additionwas added
2. customThe catalyst was removed by filtration
3. customthe solvent was evaporated from the filtrate
4. customto leave a crude oil which
5. distillationwas purified by kugelrohr distillation (115° C. at 0.2 mm pressure)