Isopropylamine → HCID 13851513, compound

HRID 1074459Notes

Reaction equation

HRID 1074459 reaction equation
[O:1]1[CH:3]([CH2:4][O:5][C:6]2[CH:17]=[CH:16][C:9]3[C:10](=[O:15])[CH:11]=[C:12]([CH3:14])[O:13][C:8]=3[CH:7]=2)[CH2:2]1.[CH3:18][CH:19]([NH2:21])[CH3:20]>C(O)C>[CH3:14][C:12]1[O:13][C:8]2[CH:7]=[C:6]([O:5][CH2:4][CH:3]([OH:1])[CH2:2][NH:21][CH:19]([CH3:20])[CH3:18])[CH:17]=[CH:16][C:9]=2[C:10](=[O:15])[CH:11]=1

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 20496738HCID 20496738, compound

Product 1

HCID 13851513HCID 13851513, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.7 g 1,2-epoxy-3-(2-methyl-4H-1-benzopyrane-4-one-7-yloxy)-propane and 2.5 cm3 2-propylamine were boiled in 40 cm3 ethanol for 2 hours; the process of example 9 (a) was followed. 4.3 g 1-(2-methyl-4H-1-benzopyrane-4-one-7-yloxy)-3-(1-methylethyl-amino)-2-propanol (m.p. 80°-82° C.) was obtained in the form of a base.

Sources & evidence

ORD record
ord-e4573d5cd4e24a11ad76dc6742e02d59
Source dataset
uspto-grants-1983_07
Patent number
US04391821

Reaction notes

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