3,4-Dichlorobenzyl chloride → HCID 20495823, compound

Participants

Reaction Steps

This ester was then reacted with 3,4-dichlorobenzyl chloride in an analogous manner to that described in part (i) and (ii) above. There was then obtained methyl 2-(3,4-dichlorobenzyl)-6-chloro-1,2-dihydro-1-oxophthalazin-4-ylcarboxylate, m.p. 168°-170° C. (recrystallised from toluene) in 45% yield. This ester was then hydrolysed as described in part (i) above to give 2-(3,4-dichlorobenzyl)-6-chloro-1,2-dihydro-1-oxophthalazin-4-ylcarboxylic acid, m.p. 222°-223° C. (recrystallised from ethanol) in 60% yield.

Provenance & Evidence