Methyl vinyl ketone → HCID 20496039, compound

HRID 1074564Notes

Reaction equation

HRID 1074564 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[CH:5]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.[CH:17]([C:19]([CH3:21])=[O:20])=[CH2:18]>>[CH:11]1([C:5]2[CH:6]=[CH:7][C:8]([CH2:18][CH2:17][C:19](=[O:20])[CH3:21])=[CH:9][CH:10]=2)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 6570Methyl vinyl ketoneHCID 13229CyclohexylbenzeneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 20496039HCID 20496039, compound

Procedure

To a stirred solution of aluminium chloride (0.15 mole) in cyclohexylbenzene (0.5 mole) at 10°-15° C. was added dropwise methyl vinyl ketone. The resulting mixture was left overnight at room temperature and worked up as above. The crude ketone was purified by distillation, b.p. 150-60 (2 mm), followed by column chromatography using silica as support and petrol/ethyl acetate as eluants.

Workup

  1. distillationThe crude ketone was purified by distillation, b.p

Sources & evidence

ORD record
ord-d29ffe4156c24438a5f84b3831d0715f
Source dataset
uspto-grants-1983_07
Patent number
US04393079

Reaction notes

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