Water → 4-(p-Allyloxyphenyl)-2-butanone

HRID 1074567Notes

Reaction equation

HRID 1074567 reaction equation
[OH:1][C:2]1[CH:12]=[CH:11][C:5]([CH2:6][CH2:7][C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[OH-].[K+].[CH2:15](Br)[CH:16]=[CH2:17].O>C(O)C>[CH2:17]([O:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH2:7][C:8](=[O:10])[CH3:9])=[CH:11][CH:12]=1)[CH:16]=[CH2:15]

Participants

6

Reactant 4

HCID 962WaterHCID 7841Allyl bromideHCID 14797Potassium HydroxideHCID 216484-(4'-Hydroxyphenyl)-2-butanone

Product 1

HCID 247087754-(p-Allyloxyphenyl)-2-butanone

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

p-Hydroxy benzylacetone (1.5 g.), KOH (6 g.) and allyl bromide (1.2 g.) were stirred in ethanol (50 ml) overnight. Water was added and the mixture extracted with ether, which was evaporated to give the compound (1.6 g.) as an oil purified by column chromatography.

Workup

  1. extractionthe mixture extracted with ether, which
  2. customwas evaporated
  3. customto give the compound (1.6 g.) as an oil
  4. custompurified by column chromatography

Sources & evidence

ORD record
ord-f485d3eb0389473c9447579dbc766b96
Source dataset
uspto-grants-1983_07
Patent number
US04393079

Reaction notes

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