HCID 13066908, compound → HCID 13066910, compound

Participants

Reaction Steps

By condensing 1,4-dimethoxy-2-methyl-3-(4-iodobutyl)naphthalene (3.84 g, 10 mmole) with 1-(2-tetrahydropyranyloxy)-2,7-octadiyne (2.10 g, 10 mmole) in accordance with the procedure of the above Reference Example 46, there was produced 1,4-dimethoxy-2-methyl-3-(12-hydroxy-5,10-dodecadiynyl)naphthalene (2.78 g, 73.5%, oily product). 1,4-Dimethoxy-2-methyl-3-(4-iodobutyl)naphthalene [δ1.5 to 2.2(4H), 2.40(3H), 2.82(2H), 3.23(2H), 3.84(3H), 3.87 (3H), 7.3 to 7.5(2H), 7.8 to 8.1(2H)] as utilized in this Reference Example was produced from 1,4-dimethoxy-2-methyl-3-(4-hydroxybutyl)naphthalene [oily substance, NMR (CDCl3), δ1.5 to 1.8(5H), 2.39(3H), 2.81(2H), 3.67(2H), 3.84(3H), 3.87(3H), 7.3 to 7.5(2H), 7.9 to 8.1(2H)] in accordance with the procedure described in Japanese Patent Application No. 49433/'80.

Provenance & Evidence