Water → 4-Chloro-6-aminobenzimidazolone

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

2,4-Dinitro-6-chloroaniline 2.7 g (12.5 m moles), selenium 1.98 g (25.0 m moles), water 1.6 ml (89 m moles), triethylamine 5.0 g (50 m moles) and tetrahydrofuran 100 ml were placed in a 200-ml capacity autoclave, and stirred at a temperature of 80° C. for five hours under carbon monoxide of 20 Kg/cm2. The reaction mixture obtained was worked up in the same manner as in EXAMPLE 1, to provide 4-chloro-6 -aminobenzimidazolone in 84% yield.

Herkunft & Nachweise