Diethyl Ether → HCID 178524973, compound

HRID 1074633Notes

Reaction equation

HRID 1074633 reaction equation
[O:1]1[CH:12]([C:13]([O:15]C2CCCCC2)=[O:14])[CH:2]1[C:3]([O:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:4].[OH-].[K+:23].C(OCC)C>C1(O)CCCCC1.CO>[O:1]1[CH:12]([C:13]([OH:15])=[O:14])[CH:2]1[C:3]([OH:5])=[O:4].[CH:6]1([K:23])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1

Participants

6

Reactant 3

HCID 3283Diethyl EtherHCID 14797Potassium HydroxideHCID 13174258HCID 13174258, compound

Product 1

HCID 178524973HCID 178524973, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 7966CyclohexanolSolvent

Procedure

To a solution of 2.5 g (0.0085 mole) of dicyclohexyl epoxysuccinate dissolved in 40 ml of cyclohexanol, a solution of 0.4 g of potassium hydroxide dissolved in 3 ml of methanol was added dropwise at room temperature. After the mixture had been stirred for 2 hours, to this, 300 ml of ethyl ether was added. Then, the mixture was allowed to stand overnight at about 5° C. The precipitate thus formed was filtered and recrystallized from ethanol-ether mixture to give cyclohexyl potassium epoxysuccinate (EP-2) as colorless needles. Yield 1.2 g (48%), m.p. 187°-189° C.

Workup

  1. additionwas added dropwise at room temperature
  2. waitto stand overnight at about 5° C
  3. customThe precipitate thus formed
  4. filtrationwas filtered
  5. customrecrystallized from ethanol-ether mixture

Sources & evidence

ORD record
ord-4412a4d60d0b4a9d8b3086684cf73dae
Source dataset
uspto-grants-1983_07
Patent number
US04393228

Reaction notes

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