1-(Cyclododec-1-en-1-yl)ethan-1-one → HCID 53843174, compound

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Reaction Steps

30 g of the 1-acetyl-1-cyclododecene obtained as described in Example 2 are dissolved in 100 ml of ethanol and 3 g of sodium borohydride are added in portions. The reaction temperature is kept at 30° C. by cooling. After a further hour of reaction time at room temperature, the alcohol is distilled off under reduced pressure at 50° C. and the residue is hydrolyzed with ice-cold 2 N sulfuric acid. The methyl-1-cyclododecen-1-yl-carbinol obtained is isolated by extraction with ether, and distillation. Boiling point=98°-100° C./0.01 mm Hg, nD25 =1.5014; 29 g yield (95% of theory)).

Provenance & Evidence