HCID 12914084, compound → HCID 12914091, compound

Participants

Reaction Steps

A solution of 0.2 g of (R)-1-t-butoxy-2,3-bis-(diphenylphosphino)propane (see Example 6) in 25 ml of anhydrous trifluoroacetic acid under argon atmosphere is stirred at room temperature for 14 hours. The trifluoroacetic acid is removed under reduced pressure. The residue is dissolved in 20 ml of dichloromethane, and washed with 5% sodium bicarbonate solution and then with water. The solvent is removed under reduced pressure and the residue is dried to yield 0.16 g of (R)-1,2-bis-(diphenylphosphino)propane-3-ol (see Formula (L) of Scheme 2) in the form of a sticky solid.

Provenance & Evidence