HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-(2-aminothiazol-4-yl)2-n-hexyloxyiminoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | Ethyl 4-chloro-2-[(hexyloxy)imino]-3-oxobutanoate | HCID 54042766 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 2-(2-aminothiazol-4-yl)2-n-hexyloxyiminoacetate | HCID 53940552 | 49% |
Reaction Steps
Ethyl 2-n-hexyloxyimino-4-chloro-3-oxobutyrate (syn isomer, 55.6 g,), thiourea (15.2 g.), sodium acetate 3-hydrate (27.2 g.), ethanol (280 ml.) and water (140 ml.) were treated in a similar manner to that of Example F-(3) to give ethyl 2-(2-aminothiazol-4-yl)-2-n-hexyloxyiminoacetate (syn isomer, 29.3 g.), mp 77° to 78° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04393059 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-a0d2f592d77649fea0e84eb85a2b25b1 |
| Source note | uspto-grants-1983_07 |