Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Acetylbutyric acid → 1-(3'-Amino-4',6'-dimethylphenyl)-6-methyl-piperidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Acetylbutyric acid | HCID 18407 | — |
| 반응물 | 4,6-Diamino-1,3-m-xylene | HCID 854386 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-(3'-Amino-4',6'-dimethylphenyl)-6-methyl-piperidin-2-one | HCID 20494961 | — |
반응 단계
A solution of 65 g (0.5 mol) of 5-oxo-caproic acid and 70 g (0.51 mol) of 3-amino-4,6-dimethylaniline in 300 ml of methanol is hydrogenated at 130°-140° in the presence of Raney nickel. Yield: 110 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04394156 |
| 출처 데이터셋 | uspto-grants-1983_07 |
| ORD ID | ord-497238827bda42708458be9f6b673913 |
| 출처 메모 | uspto-grants-1983_07 |