HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Levulinic Acid → 1-(3'-Amino-4',6'-dimethylphenyl)-5-methyl-pyrrolidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Levulinic Acid | HCID 11579 | — |
| Edukt | 4,6-Diamino-1,3-m-xylene | HCID 854386 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | Platinum oxide (PtO) | HCID 82844 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(3'-Amino-4',6'-dimethylphenyl)-5-methyl-pyrrolidin-2-one | HCID 12833274 | 80% |
Reaktionsschritte
A suspension of 0.2 g of platinum oxide in 25 ml of ethanol is treated with hydrogen and a solution of 34.8 g (0.3 mol) of levulinic acid and 85 g (0.62 mol) of 3-amino-4,6-dimethylaniline in 300 ml of ethanol is then added. The hydrogenation is carried out at room temperature. The desired pyrrolidinone derivative is obtained in a yield of about 80%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04394156 |
| Quelldatensatz | uspto-grants-1983_07 |
| ORD ID | ord-dc3c4e10beef4146bfdccf5ba09316b3 |
| Quellennotiz | uspto-grants-1983_07 |