HCID 20494998, compound → HCID 20495001, compound

Participants

Reaction Steps

48.3 g (0.165 mol) 1-(3'-nitro-4',6'-dimethylphenyl)-3-cyano-4,6-dimethyl-2-pyridone are dissolved in 1 liter of dimethylformamide and, after adding of 5 g palladium/charcoal catalyst, hydrogenated at normal pressure and 15°-20° C. The catalyst is filtered off and the filtrate is concentrated by evaporation. The residue is treated with hexane and dried. Yield: 42.0 g (95.3%) 1-(3'-amino-4',6'-dimethylphenyl)-3-cyano-4,6-dimethyl-2-pyridone, mp. 218°-219° C.

Provenance & Evidence