1H-1,2,4-Triazole → HCID 17993791, compound

Participants

Reaction Steps

α-Chloro-p-chloroanisole (10.6 g) and 1,2,4-triazole (12.4 g) in acetonitrile (120 ml) were refluxed for 48 hours. After cooling to room temperature, triazole hydrochloride was filtered off and acetonitrile removed at reduced pressure to give a sticky gum which was extracted with hot petroleum ether (80°-100°) and allowed to cool slowly to give colourless prisms of the title compound.

Provenance & Evidence