HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3,4-dihydro-8-ethoxycarbonyloxy-3-hydroxy-2H-1-benzopyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 3,4-Dihydro-2H-1-benzopyran-3,8-diol | HCID 13318094 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3,4-dihydro-8-ethoxycarbonyloxy-3-hydroxy-2H-1-benzopyran | HCID 16744790 | 100.2% |
Reaction Steps
23.05 g of 3,4-dihydro-3,8-dihydroxy-2H-1-benzopyran was dissolved in 320 ml of tetrahydrofuran, and 16.7 g of triethylamine was added. With stirring under cooling, a solution of 17.9 g of ethyl chloroformate in 100 ml of tetrahydrofuran was added dropwise. The mixture was worked up in the same way as in Example 1 to give 33.1 g (yield 100%) of 3,4-dihydro-8-ethoxycarbonyloxy-3-hydroxy-2H-1-benzopyran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04394382 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-f3a9b2a573794a0288c38f77bca6eab7 |
| Source note | uspto-grants-1983_07 |