Ethyl bromoacetate → HCID 20495240, compound

Participants

Reaction Steps

0.82 g of 8-benzyloxy-3,4-dihydro-6-hydroxy-2H-1-benzopyran (0.82 g) was dissolved in 300 ml of anhydrous acetone, and 0.88 g of anhydrous potassium carbonate and 1.07 g of ethyl bromoacetate were added. The mixture was stirred under reflux for 7 hours. After the reaction, the insoluble matter was removed by filtration, and the solvent was distilled off. The residue was dissolved in 50 ml of chloroform, washed with water and dried. The solvent was distilled off to give 1.09 g (yield 99.5%) of 8-benzyloxy-3,4-dihydro-6-ethoxycarbonylmethoxy-2H-1-benzopyran.

Provenance & Evidence