HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 8-Chlorodibenzo[b,f]thiepin-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 8-Chloro-3-cyanodibenzo[b,f]thiepin | HCID 13151889 | — |
| Product | 8-Chlorodibenzo[b,f]thiepin-3-carboxylic acid | HCID 13151891 | — |
Reaction Steps
550 Mg. 8-chloro-3-cyanodibenzo[b,f]thiepin is refluxed for 16 hours in a mixture of 15 cc. acetic acid and 15 cc. 50% aqueous sulfuric acid. The reaction mixture is cooled down and the product filtered, washed with water, and dried to yield 485 mg. (82% of the pure acid, m.p. 302°-304° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04394515 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-db75df64a3bc4489a02a7e0567086716 |
| Source note | uspto-grants-1983_07 |