HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 3-Bromomethyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | 3-Hydroxymethyl-10,11-dihydro-11-oxodibenzo[b,f]-thiepin | HCID 20270242 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Bromomethyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin | HCID 20270268 | — |
Reaction Steps
Dissolve 4.43 g. of the alcohol of Step 1 in 100 cc. of benzene and add 1 cc. (10.5 mmole) of phosphorous tribromide. Stir at room temperature for 1 hour, add water and then dilute with toluene. Wash three times with water, dry and strip to a solid residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04394515 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-60b2888817de4f5d8cebf42fa7478757 |
| Source note | uspto-grants-1983_07 |