HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dimethylpyrimidin-2-ol → 5-Chloro-4,6-dimethyl-pyrimidin-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dimethylpyrimidin-2-ol | HCID 9508 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 5-Chloro-4,6-dimethyl-pyrimidin-2-ol | HCID 20494280 | — |
Reaction Steps
A solution of chlorine (0.01 mol) in acetic anhydride (100 ml) was added to a solution of 4,6-dimethylpyrimid-2-one (0.008 mol) in acetic anhydride (100 ml) and the solution left at room temperature for 1 hr before the solid precipitate was collected and recrystallised from water; m.p. 235° C. (decomp.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04395406 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-c1dc9053935c423e85228be8e8522698 |
| Source note | uspto-grants-1983_07 |