Allyl bromide → HCID 178460812, compound

Participants

Reaction Steps

Allyl bromide (0.013 mol) was added to a solution of 5-fluoro-4-thiouracil (0.01 mols), 8.73 mols NaOH (25 mls) and the reaction mixture stirred at room temperature for 5 hrs. The reaction mixture was then extracted with chloroform (2×5 ml), before the aqueous solution was acidified with HCl when the titled compound was precipitated; yield 40%, m.p. 150°-152° C. (water). (Found: C, 44.87; H, 3.84. Calc. for C7H7SFN2O; C, 45.15; H, 3.80).

Provenance & Evidence