Acetic Acid → HCID 12763560, compound

HRID 1075182Notes

Reaction equation

HRID 1075182 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]Cl)=[C:6]([C:12]([Cl:15])([Cl:14])[Cl:13])[CH:5]=1)([O-:3])=[O:2].C[N:17]1[C:22]([SH:23])=[C:21]([C:24]#[N:25])[C:20]([CH3:26])=[CH:19][CH2:18]1.[C:27](O)(=O)C>>[CH3:26][C:20]1[CH:19]=[C:18]([CH3:27])[N:17]=[C:22]([S:23][S:10][C:7]2[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][C:6]=2[C:12]([Cl:15])([Cl:14])[Cl:13])[C:21]=1[C:24]#[N:25]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 127635554-Nitro-2-trichloromethylbenzenesulfenyl chlorideHCID 20494588HCID 20494588, compound

Product 1

HCID 12763560HCID 12763560, compoundYield 67%

Procedure

61.4 g of 4-nitro-2-trichloromethylbenzenesulfenyl chloride, dissolved in 500 ml of glacial acetic acid, are reacted with 33 g of 1,4-dimethyl-5-cyano-6-mercaptopyridine at 20° C. After 2 hours, the solution is filtered, 500 ml of water are added and the precipitate formed is filtered off, washed with 10% strength sodium carbonate solution and with ether, and dried over potassium hydroxide. 58 g (67% of theory) of 4,6-dimethyl-3-cyano-pyridin-2-yl-dithio-(4-nitro-2-trichloromethylbenzene), of melting point 132° C., are obtained.

Workup

  1. filtrationthe solution is filtered
  2. addition500 ml of water are added
  3. customthe precipitate formed
  4. filtrationis filtered off
  5. washwashed with 10% strength sodium carbonate solution and with ether
  6. dry with materialdried over potassium hydroxide

Sources & evidence

ORD record
ord-2263ab360bda4e248978d60d98a5f95c
Source dataset
uspto-grants-1983_07
Patent number
US04395415

Reaction notes

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