Methyl Acrylate → HCID 13180328, compound

Participants

Reaction Steps

1 ml of benzyltrimethylammonium hydroxide is added to a suspension of 8 g of 7-chloro-1,2-dihydro-2-oxo-3-phenylquinoline in 21.3 ml of methyl acrylate at 40° to 50° C., under nitrogen, the mixture is stirred at this temperature for 31/2 hours and the excess methyl acrylate is then distilled off in vacuo. The solid residue is dissolved in 100 ml of methylene chloride and the solution is washed with 2 N acetic acid, sodium bicarbonate solution and water. After drying the organic phase over sodium sulphate and distilling off the solvent, the residue is recrystallised from cyclohexane. 8.0 g of the title compound of m. 122°-124° C. are obtained.

Provenance & Evidence