Formaldehyde → HCID 20494488, compound

HRID 1075205Notes

Reaction equation

HRID 1075205 reaction equation
[CH3:1][CH:2]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:20]=O>C(O)=O>[CH3:20][N:9]([CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH:2]([CH3:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 20494522HCID 20494522, compound

Product 1

HCID 20494488HCID 20494488, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

4-Phenylbutyryl chloride was reacted with 1-methylheptylamine to provide N-(1-methylheptyl)-4-phenylbutyramide, which, when reduced by reaction with dibroane in tetrahydrofuran, provided N-(1-methylheptyl)-4-phenylbutylamine. The amine so formed was reacted with formic acid and formaldehyde to give N-methyl-N-(1-methylheptyl)-4-phenylbutylamine.

Sources & evidence

ORD record
ord-32521194e0e1480d8dad4baab23cedd7
Source dataset
uspto-grants-1983_07
Patent number
US04395410

Reaction notes

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