Phenyl isocyanate → HCID 12785879, compound

Participants

Reaction Steps

2 g of 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepine-2-thione are reacted with 0.8 g of sodium bicarbonate and 0.7 g of hydroxylammonium chloride, analogously to Example 16. After stirring for 8 hours at room temperature, 0.8 ml of phenyl isocyanate are added, and the mixture is stirred for 1/2 an hour and precipitated with water; the oil produced is crystallized by means of ethanol. Recrystallization from ethanol yields 2 g of yellow crystals of melting point 201° to 203° C.

Provenance & Evidence