3,4-Dichlorophenyl isocyanate → HCID 20494329, compound

HRID 1075215Notes

Reaction equation

HRID 1075215 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:14]2[CH:15]=[C:16]([N+:19]([O-:21])=[O:20])[CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([NH:22][O:23]C(=O)NC2C=CC=CC=2)[CH2:10][N:9]=1.[Cl:33][C:34]1[CH:35]=[C:36]([N:41]=[C:42]=[O:43])[CH:37]=[CH:38][C:39]=1[Cl:40]>C(O)C>[Cl:33][C:34]1[CH:35]=[C:36]([NH:41][C:42]([O:23][NH:22][C:11]2[CH2:10][N:9]=[C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])[C:14]3[CH:15]=[C:16]([N+:19]([O-:21])=[O:20])[CH:17]=[CH:18][C:13]=3[N:12]=2)=[O:43])[CH:37]=[CH:38][C:39]=1[Cl:40]

Participants

4

Reactant 2

HCID 76073,4-Dichlorophenyl isocyanateHCID 12785879HCID 12785879, compound

Product 1

HCID 20494329HCID 20494329, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1 g of 5-(2-chlorophenyl)-2-hydroxyamino-7-nitro-3H-1,4-benzodiazepine of Example 18 is reacted with 0.56 g of 3,4-dichlorophenyl isocyanate and worked up as in Example 18. Yield: 1.1 g, melting point: 190° to 192° C. decomposition (from ethanol).

Sources & evidence

ORD record
ord-c235089487aa400bbfb9479f81d2abec
Source dataset
uspto-grants-1983_07
Patent number
US04395409

Reaction notes

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