2-(7-Bromoimidazo[1,2-b][1,2,4]triazin-3-yl)propan-2-ol → 7-(4-Fluoro-2-methoxyphenyl)-α,α-dimethylimidazo[1,2-b][1,2,4]triazine-3-methanol

HRID 107533Notes

Reaction equation

HRID 107533 reaction equation
[Br:19][c:20]1[cH:21][n:22][c:23]2[n:24]1[n:25][cH:26][c:27]([C:29]([CH3:30])([CH3:31])[OH:32])[n:28]2.[F:1][c:2]1[cH:3][c:4]([O:17][CH3:18])[c:5]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([O:17][CH3:18])[c:5](-[c:20]2[cH:21][n:22][c:23]3[n:24]2[n:25][cH:26][c:27]([C:29]([CH3:30])([CH3:31])[OH:32])[n:28]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 112076032-(7-Bromoimidazo[1,2-b][1,2,4]triazin-3-yl)propan-2-olHCID 222400914-Fluoro-2-Methoxybenzeneboronic acid pinacol ester, 96%

Product 1

HCID 222400807-(4-Fluoro-2-methoxyphenyl)-α,α-dimethylimidazo[1,2-b][1,2,4]triazine-3-methanol

Sources & evidence

ORD record
ord-6b537bd1b1114832a1c1db4d13d1e62c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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