N-(3-(Pyridin-2-yl)phenyl)acetamide → N-Acetyl 3-(2-(dimethylamino)-5-pyrimidyl)aniline

HRID 1075456Notes

Reaction equation

HRID 1075456 reaction equation
[CH3:1][N:2]([CH3:16])[C:3]1[N:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]([CH:13]=[CH:14][CH:15]=2)[NH2:12])=[CH:5][N:4]=1.[C:17](NC1C=CC=C(C2C=CC=CN=2)C=1)(=[O:19])[CH3:18]>>[C:17]([NH:12][C:11]1[CH:13]=[CH:14][CH:15]=[C:9]([C:6]2[CH:7]=[N:8][C:3]([N:2]([CH3:16])[CH3:1])=[N:4][CH:5]=2)[CH:10]=1)(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 53737528N-(3-(Pyridin-2-yl)phenyl)acetamideHCID 538349803-(2-(Dimethylamino)-5-pyrimidyl)aniline

Product 1

HCID 53880835N-Acetyl 3-(2-(dimethylamino)-5-pyrimidyl)aniline

Procedure

2h is acetylated as described for 2g in Example 5 to yield 2i. Mp 183-188° C.

Sources & evidence

ORD record
ord-3382478f156a43c3b9280fca816a35be
Source dataset
uspto-grants-1999_05
Patent number
US05902813

Reaction notes

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