N-Acetyl 3-(2-(dimethylamino)-5-pyrimidyl)aniline → N-(3-(2-(Dimethylamino)pyrimid-5-yl)phenyl)-2-nitro-4-(1-pyrrolyl)aniline

HRID 1075459Notes

Reaction equation

HRID 1075459 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([N:10]2[CH:14]=[CH:13][CH:12]=[CH:11]2)[CH:7]=[CH:6][C:5]=1F)([O-:3])=[O:2].C([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([C:26]2[CH:27]=[N:28][C:29]([N:32]([CH3:34])[CH3:33])=[N:30][CH:31]=2)[CH:21]=1)(=O)C>>[CH3:33][N:32]([CH3:34])[C:29]1[N:28]=[CH:27][C:26]([C:22]2[CH:21]=[C:20]([NH:19][C:5]3[CH:6]=[CH:7][C:8]([N:10]4[CH:14]=[CH:13][CH:12]=[CH:11]4)=[CH:9][C:4]=3[N+:1]([O-:3])=[O:2])[CH:25]=[CH:24][CH:23]=2)=[CH:31][N:30]=1

Participants

3

Reactant 2

HCID 53880835N-Acetyl 3-(2-(dimethylamino)-5-pyrimidyl)anilineHCID 541021862-Nitro-4-(1-pyrrolyl)fluorobenzene

Product 1

HCID 53636071N-(3-(2-(Dimethylamino)pyrimid-5-yl)phenyl)-2-nitro-4-(1-pyrrolyl)anilineYield 20%

Procedure

N-(3-(2-(Dimethylamino)pyrimid-5-yl)phenyl)-2-nitro-4-(1-pyrrolyl)aniline (3f) was prepared analogously from 1a and 2i. Yield: 20%. Mp 166-168° C.

Sources & evidence

ORD record
ord-90d79eba413b45509923e91db906e273
Source dataset
uspto-grants-1999_05
Patent number
US05902813

Reaction notes

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