Aspirin → 4'-Bromosalicylanilide

HRID 1075580Notes

Reaction equation

HRID 1075580 reaction equation
C([O:4][C:5]1[C:6](=[CH:10][CH:11]=[CH:12][CH:13]=1)[C:7]([OH:9])=O)(=O)C.[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1>>[Br:14][C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:7](=[O:9])[C:6]2[CH:10]=[CH:11][CH:12]=[CH:13][C:5]=2[OH:4])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 2244AspirinHCID 78074-Bromoaniline

Product 1

HCID 758174'-Bromosalicylanilide

Procedure

This compound was obtained as a white solid starting from acetylsalicyclic acid and 4-bromoaniline using the same procedure described in example 5.

Workup

  1. customThis compound was obtained as a white solid

Sources & evidence

ORD record
ord-b71acd01b980461fbbaa243e392d8d06
Source dataset
uspto-grants-1999_05
Patent number
US05905090

Reaction notes

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