Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 10756Generated: October 26, 2026

Dichloromethane → Diisopropylethylamine

https://huagongshe.com/reaction/10756

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantLevulinic AcidHCID 11579—
ReactantDiisopropylcarbodiimideHCID 12734—
ProductDiisopropylethylamineHCID 81531—

Reaction Steps

addition of activated levulinic acid (activated as the symmetric anhydride with 0.5 equivalents of DIC in DCM for 5-10 min)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07094871B2
Source datasetuspto-grants-2006_08
ORD IDord-ffec451764134a1db4236c62aaba0bd9
Source noteuspto-grants-2006_08