HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-4-(tert-butoxy)-3-{[(tert-butoxy)carbonyl]amino}-4-oxobutanoic acid → N-[2-(N-tert-Butyloxycarbonyl-O-tert-butyl-L-aspartyl-L-alanyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-4-(tert-butoxy)-3-{[(tert-butoxy)carbonyl]amino}-4-oxobutanoic acid | HCID 7010517 | — |
| Reactant | N-(2-L-alanyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-octadecyl-oleamide | HCID 86755189 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[2-(N-tert-Butyloxycarbonyl-O-tert-butyl-L-aspartyl-L-alanyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamide | HCID 131721267 | 27% |
Reaction Steps
from N-(2-L-alanyl-amino-2-deoxy-β-D-glucopyranosyl)-N-octadecyl-oleamide and N-tert-butyloxycarbonyl-O-tert-butyl-L-aspartic acid. Yield 27%. [α]D =-1.5° (c=0.55, dichloromethane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05905071 |
| Source dataset | uspto-grants-1999_05 |
| ORD ID | ord-9bd83a5aff4e4c3faed06be4adcf995d |
| Source note | uspto-grants-1999_05 |