Ethyl bromoacetate → HCID 54292818, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-(8-benzyloxyquinol-5-ylmethylen)-2-oxindole (140 mg, 0.37 mmol) in acetone (10 ml) was added 2-bromoacetic acid ethyl ester (151 mg, 0.9 mmol) and anhydrous potassium carbonate (150 mg) and the reaction mixture was stirred for 8 h at 50° C. Then the mixture was concentrated under vacuum, the residue taken up with dichloromethane, the organic phase washed several times with water, dried and evaporated. The residue was crystallized from ethyl acetate to give 150 mg (87% yield) of title compound.

Provenance & Evidence