4-Amino-3,5-dichlorobenzotrifluoride → HCID 15405415, compound

HRID 1075690Notes

Reaction equation

HRID 1075690 reaction equation
ClC1C=C(C(F)(F)F)C=C(Cl)C=1N.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](C(CC#N)C(=O)C)(=[O:23])=[O:22])=[CH:17][CH:16]=1.ClC1C=CC(S([C:41]([N:48]=[N:49][C:50]2[C:55]([Cl:56])=[CH:54][C:53]([C:57]([F:60])([F:59])[F:58])=[CH:52][C:51]=2[Cl:61])([CH2:45][C:46]#[N:47])[C:42](=[O:44])[CH3:43])(=O)=O)=CC=1>>[C:42]([C:41]1[C:45]([S:21]([C:18]2[CH:19]=[CH:20][C:15]([Cl:14])=[CH:16][CH:17]=2)(=[O:23])=[O:22])=[C:46]([NH2:47])[N:49]([C:50]2[C:51]([Cl:61])=[CH:52][C:53]([C:57]([F:58])([F:60])[F:59])=[CH:54][C:55]=2[Cl:56])[N:48]=1)(=[O:44])[CH3:43]

Participants

4

Reactant 3

HCID 1410944-Amino-3,5-dichlorobenzotrifluorideHCID 18702190HCID 18702190, compoundHCID 18702192HCID 18702192, compound

Product 1

HCID 15405415HCID 15405415, compound

Procedure

A process according to claim 1, comprising reacting the hydrogensulfate diazonium salt of 2,6-dichloro-4-trifluoromethylaniline with 3-(4-chlorophenylsulfonyl)-4-cyanobutan-2-one, and then subjecting the resultant 3-(4-chlorophenylsulfonyl)-3-(2,6-dichloro-4-trifluoromethylphenylazo)-4-cyanobutan-2-one to rearrangement to afford 3-acetyl-5-amino-4-(4-chlorophenyl)sulfonyl-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole.

Sources & evidence

ORD record
ord-b4edb2eee13a4daca75493749ea512a6
Source dataset
uspto-grants-1999_05
Patent number
US05907041

Reaction notes

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