Ethanol → HCID 86754078, compound
Reaction equation
C([NH:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10])(=O)C.[Na+:12].[OH-].[Na+].CCO>O>[NH2:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10].[Na+:12]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 100 °C
Procedure
52 g of sodium 5-acetylamino-3-oxapentanoate were dissolved in 200 ml of water. 11.4 g of NaOH were added at 20° C., and the reaction mixture was then heated at 100° C. for 8 h until precursor was no longer detectable. Then 200 ml of EtOH were added and the pH was adjusted to about 6, resulting in pure crystals of sodium 5-amino-3-oxapentanoate. The crude product resulting after removal of the solvent by distillation as a mixture with sodium acetate weighing 63.3 g (corresponding to 100% of theory) could be employed without prior precipitation for the subsequent reaction.
Sources & evidence
- ORD record
- ord-73112dd8f6c24967aaee3dc92f68f0da
- Source dataset
- uspto-grants-1999_05
- Patent number
- US05907055
Reaction notes
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