HCID 21540634, compound → HCID 21540640, compound

HRID 1075728Notes

Reaction equation

HRID 1075728 reaction equation
[Cl:1][C:2]1[C:3]([C:16]([F:19])([F:18])[F:17])=[CH:4][C:5]2[N:9]=[CH:8][N:7]([CH2:10][CH3:11])[C:6]=2[C:12]=1[N+:13]([O-])=O>[Pt]=O>[NH2:13][C:12]1[C:6]2[N:7]([CH2:10][CH3:11])[CH:8]=[N:9][C:5]=2[CH:4]=[C:3]([C:16]([F:18])([F:19])[F:17])[C:2]=1[Cl:1]

Participants

3

Reactant 1

HCID 21540634HCID 21540634, compound

Product 1

HCID 21540640HCID 21540640, compound

Reagents, catalysts & solvents 1

HCID 82844Platinum oxide (PtO)Catalyst

Procedure

6-Chloro-1-ethyl-7-nitro-5-trifluoromethylbenzimidazole (3.54g.; 0.012 mole; m.p. 126.5°-128°C.) was hydrogenated in the presence of platinum oxide catalyst in accordance with the procedure of Example IV. The product was obtained as a white crystalline solid (1.54g.; 48.9%) which, after recrystallization from a CCl4 --CHCl3 mixture, melts at 191.5°-193°C.

Workup

  1. customThe product was obtained as a white crystalline solid (1.54g.; 48.9%) which
  2. customafter recrystallization from a CCl4

Sources & evidence

ORD record
ord-4ab4988e7e6441f38fdcc3eceb8b7bcd
Source dataset
uspto-grants-1976_05
Patent number
US03954438

Reaction notes

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