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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1075759Generated: November 1, 2026

Sodium Hydroxide → 1-Cyanocyclobutane-1-carboxylic acid

https://huagongshe.com/reaction/1075759

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactantethyl 1-cyanocyclobutanecarboxylateHCID 275343—
SolventMethanolHCID 887—
Product1-Cyanocyclobutane-1-carboxylic acidHCID 21540878—

Reaction Steps

20 g (0.131 mol) of 1-cyano-1-cyclobutanecarboxylic acid ethyl ester are dissolved in 60 ml of methanol and saponified with 40 ml of 4 N NaOH for about 12 hours at 23° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03954730
Source datasetuspto-grants-1976_05
ORD IDord-7f402f4d45f44f119ad77a11aab3bd83
Source noteuspto-grants-1976_05