Iodine → HCID 12934702, compound

Participants

Reaction Steps

A solution of 13.1 g of 2-methylindole in 175 ml of warm methanol is added to a well-stirred solution of 50 g of potassium iodide and 25.4 g of iodine in 150 ml of water. This mixture is further treated with a hot solution of 10.2 g of 2-imidazolidinethione in 150 ml of warm methanol. The reaction is carried out and worked up in the manner described under Example 1 to yield 2-methyl-3-(2-imidazolin-2-ylthio)-indole hydriodide which melts at 227°-228° (with decomposition) after recrystallization from a mixture of methanol, ethyl acetate and ether.

Provenance & Evidence