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1-Ethylpiperazine → 6-[p-(4-Ethyl-1-piperazinyl)phenyl]-1,2-dihydro-2-oxonicotinonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Ethylpiperazine | HCID 79196 | — |
| 反応物 | 6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | HCID 2765203 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 6-[p-(4-Ethyl-1-piperazinyl)phenyl]-1,2-dihydro-2-oxonicotinonitrile | HCID 21404518 | — |
反応手順
From 21.4 g. of 6-(p-fluorophenyl)-1,2-dihydro-2-oxonicotinonitrile and 22.8 g. of N-ethylpiperazine in 200 ml. of dimethyl sulfoxide, there is obtained 6-[p-(4-ethyl-1-piperazinyl)phenyl]-1,2-dihydro-2-oxonicotinonitrile; m.p. 283°-285° (dec.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03954734 |
| 出典データセット | uspto-grants-1976_05 |
| ORD ID | ord-b6e2b159f8ac485599c5929af341c443 |
| 出典メモ | uspto-grants-1976_05 |