2-Chlorobenzoyl chloride → HCID 12582668, compound

HRID 1075902Notes

Reaction equation

HRID 1075902 reaction equation
ClC1C=CC=CC=1C([C:6]1[N:11]=[N:10][C:9]2[CH2:12][CH2:13][NH:14][CH2:15][C:8]=2[CH:7]=1)=O.C(O)(=O)/C=C\C(O)=O.ClC1[N:34]=[N:33]C2CCNCC=2C=1.[Cl:39][C:40]1[CH:48]=[CH:47][CH:46]=[CH:45][C:41]=1[C:42](Cl)=[O:43]>C(O)C>[Cl:39][C:40]1[CH:48]=[CH:47][CH:46]=[CH:45][C:41]=1[C:42]([N:14]1[CH2:13][CH2:12][C:9]2[N:10]=[N:11][C:6]([NH:33][NH2:34])=[CH:7][C:8]=2[CH2:15]1)=[O:43]

Participants

5

Reactant 3

HCID 691102-Chlorobenzoyl chlorideHCID 86733381HCID 86733381, compoundHCID 86733382HCID 86733382, compound

Product 1

HCID 12582668HCID 12582668, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 3-chloro-6-(o-chlorobenzoyl-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine, required as starting material, may be obtained in a manner analogous to that described in Example 8 (g), from 28.5 g of 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and 16.9 g of o-chlorobenzoyl chloride. M.P. 97°-99° (decomp., from 95% ethanol).

Workup

  1. custommay be obtained in a manner analogous to

Sources & evidence

ORD record
ord-dd18a969b6df4468872767954c7e7c67
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

Loading…