2-Naphthoyl chloride → HCID 12582684, compound

HRID 1075915Notes

Reaction equation

HRID 1075915 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1.C(O)(=O)/C=C\C(O)=O.ClC1[N:38]=[N:37]C2CCNCC=2C=1.C1C2C(=CC=CC=2)C=CC=1C(Cl)=O>C(O)C>[NH:37]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12]([C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)=[O:13])[CH2:11][C:4]=2[CH:3]=1)[NH2:38]

Participants

5

Reactant 3

HCID 752462-Naphthoyl chlorideHCID 20441559HCID 20441559, compoundHCID 86733381HCID 86733381, compound

Product 1

HCID 12582684HCID 12582684, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 3-chloro-6-(2-naphthoyl)-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine, required as starting material, is produced in a manner analogous to that described in Example 8 (g), from 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and 2-naphthoyl chloride. Reaction time 22 hours at room temperature. M.P. 167°-170° (decomp., from 95% ethanol).

Workup

  1. customis produced in a manner analogous to
  2. customReaction time 22 hours at room temperature

Sources & evidence

ORD record
ord-6f0841cc20e143a29b378151a808a616
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

Loading…