Allyl chloroformate → HCID 12582636, compound

HRID 1075925Notes

Reaction equation

HRID 1075925 reaction equation
[CH2:1]([O:4][C:5]([N:7]1[CH2:17][CH2:16][C:10]2[N:11]=[N:12][C:13](Cl)=[CH:14][C:9]=2[CH2:8]1)=[O:6])[CH:2]=[CH2:3].C(O)(=O)/C=C\C(O)=O.ClC1[N:32]=[N:31]C2CCNCC=2C=1.C(OC(Cl)=O)C=C>>[CH2:1]([O:4][C:5]([N:7]1[CH2:17][CH2:16][C:10]2[N:11]=[N:12][C:13]([NH:31][NH2:32])=[CH:14][C:9]=2[CH2:8]1)=[O:6])[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 18052Allyl chloroformateHCID 541038892-Propen-1-yl 3-chloro-7,8-dihydropyrido[4,3-c]pyridazine-6(5H)-carboxylateHCID 86733381HCID 86733381, compound

Product 1

HCID 12582636HCID 12582636, compound

Procedure

The 3-chloro-5,6,7,8-tetrahydro-6-pyrido [4,3-c]pyridazinecarboxylic acid allyl ester, required as starting material, may be obtained in a manner analogous to that described in Example 8 (g), from 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and chloroformic acid allyl ester. The oily crude product is used for the next reaction without purification.

Workup

  1. custommay be obtained in a manner analogous to

Sources & evidence

ORD record
ord-97f1b3824e6a4280acd2a8a1f5798c89
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

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