Endralazine → HCID 12582661, compound

HRID 1075936Notes

Reaction equation

HRID 1075936 reaction equation
[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][NH2:18])=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C1(=O)CCCCC1>[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][N:18]=[C:2]3[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]3)=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 47608Endralazine

Product 1

HCID 12582661HCID 12582661, compound

Reagents, catalysts & solvents 1

HCID 7967CyclohexanoneSolvent

Procedure

A suspension of 8.3 g of 6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine in 20 cc of cyclohexanone is boiled at reflux at a bath temperature of 180° for 2 hours. The title compound has a M.P. of 188°-191° (decomp., from acetonitrile).

Workup

  1. temperatureat reflux at a bath temperature of 180° for 2 hours

Sources & evidence

ORD record
ord-cd171e03859a4f06be5a85d3e678e994
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

Loading…