Cyclododecanone → HCID 20441599, compound

HRID 1075946Notes

Reaction equation

HRID 1075946 reaction equation
[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][NH2:18])=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:21]1(=O)[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>C(O)C>[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][N:18]=[C:21]3[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]3)=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 13246CyclododecanoneHCID 47608Endralazine

Product 1

HCID 20441599HCID 20441599, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A suspension of 2.7 g of 6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine and 1.8 g of cyclododecanone in 20 cc of absolute ethanol is heated on a water bath for 30 minutes, whereby a dissolution and reprecipitation clearly occurs. The resulting title compound is recrystallized from a mixture of 160 cc of methanol and 30 cc of dimethyl formamide. M.P. 222°-225° (decomp.).

Workup

  1. temperatureis heated on a water bath for 30 minutes
  2. dissolutionwhereby a dissolution and reprecipitation
  3. customThe resulting title compound is recrystallized from a mixture of 160 cc of methanol and 30 cc of dimethyl formamide

Sources & evidence

ORD record
ord-02806b0eed434e94a3992ffeae0265cc
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

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