HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → (3-Carboxypropyl)(triphenyl)phosphanium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 4-Bromobutyric acid | HCID 75809 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | (3-Carboxypropyl)(triphenyl)phosphanium bromide | HCID 10717451 | — |
Reaction Steps
Refer to Chart A. 3-Carboxypropyltriphenylphosphonium bromide is prepared by heating triphenylphosphine (156.8 g.) and 4-bromobutyric acid (100 g.) in 125 ml. of benzene at reflux for 18 hrs. The crystalline product is filtered off, washed with benzene, and recrystallzed from ethanolacetonitrile-ether, 150 g., m.p. 247°-249° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03954835 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-2e4ca44dd5d3434c8283886e47d9fd8d |
| Source note | uspto-grants-1976_05 |