HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobiphenyl → HCID 53652234, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobiphenyl | HCID 7101 | — |
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Reactant | Sodium amide | HCID 24533 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 86733398 | HCID 86733398 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 53652234 | HCID 53652234 | — |
Reaction Steps
4'-Bromo-4-biphenylyl-4-chlorophenyl ketone (74 g.), prepared by the reaction of p-chlorobenzoyl chloride and 4-bromobiphenyl in the presence of aluminium chloride, acetonitrile (12 g.) and sodamide (10 g.) were reacted in benzene by the method of Example 1 to give 3-hydroxy-3-(4'-bromo-4-biphenylyl)-3-p-chlorophenylpropionitrile, mp 160°-161°C after recrystallisation from benzene; λ max (ethanol) = 262 nm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03954869 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-af431503afce4883aba669b04a769df8 |
| Source note | uspto-grants-1976_05 |