4-tert-Butylphenol → 1,1,3,3-Tetramethylindan-5-ol

Participants

Reaction Conditions

Reaction Steps

68 g (1/2 mol) of 4-isopropyl-phenol, 150 g (1 mol) of 4-tert.-butyl-phenol and 30 g of an acid activated Fuller's earth were stirred for 5 hours at 150°C. The substance which collected in the deep cooling condenser was isobutane. After removal of the catalyst by suction filtration, fractional distillation yielded 46 g of 1,1,3,3-tetramethyl-5-hydroxy-indane in addition to phenol.

Provenance & Evidence