HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl isothiocyanate → HCID 20316739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | N-(3-aminopropyl)pyridin-2-amine | HCID 10606924 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 20316739 | HCID 20316739 | 60.3% |
Reaction Steps
A solution of 2-(3-aminopropylamino)pyridine (2.74 g.) and methyl isothiocyanate (1.46 g.) in isopropyl alcohol (50 ml.) was stirred at room temperature for 16 hours Concentration, followed by trituration of the residue under methyl ethyl ketone gave the crude product which, was recrystallised from aqueous ethanol to give N-methyl-N'-[3-(2-pyridylamino)propyl]thiourea (2.45 g.) m.p. 134°-135.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03954982 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-92baa4d8e45d4d16a79ff70ea87d3e1c |
| Source note | uspto-grants-1976_05 |