Diisopropylethylamine → HCID 6604391, compound

Participants

Reaction Steps

Pivampicillin tosylate, hydrate (13.1 g) was stirred with isopropanol (50 ml) at 0°C, while diisopropylethylamine (3.45 ml) was added dropwise. After 30 min. the crystalline precipitate was collected by filtration, washed with isopropanol (25 ml) and hexane (50 ml, bp. 60°-80°), and air-dried, yielding crystalline pivampicillin with a melting point of 114°-116°C.

Provenance & Evidence