反应详情

温度

20 °C

To a suspension of 420.6 g (2.2 mole) 2-(methoxycarbonylamino)-benzimidazole in 10 ltr chloroform a solution of 274 g (2.3 moles) phenyl cyanate in 2 ltr chloroform is added in drops while stirring at 20°C. The reaction mixture is stirred for 6 hours at room temperature and then left standing overnight. The product is then filtered and the solvent removed under vacuum. The colorless, crystalline residue is treated with ether.

1. additionis added in drops
2. stirringThe reaction mixture is stirred for 6 hours at room temperature
3. waitleft
4. filtrationThe product is then filtered
5. customthe solvent removed under vacuum
6. additionThe colorless, crystalline residue is treated with ether